Degenerative Diseases


Functional MRI (fMRI) uses many tools including Magnetic Resonance Spectroscopy (MRS) to evaluate degenerative disorders such as Alzheimer’s disease, and helps to differentiate memory loss and dementias with similar symptoms.  MRS works by calculating the ratios of select chemicals in the brain.  Different types of dementia can originate in different parts of the brain, so MRS is also able to calculate these metabolites in multiple brain regions.

MRS can be used as a stand-alone product or can be coupled with a Volumetric Analysis which can provide additional age-related markers and data for determining a treatment plan on an individual basis.

Normal

Alzheimers

Putamen Abnormal MSA

 

Treatments for Degenerative Diseases

While various pharmacological medications combined with psychotherapy have traditionally been used with some degree of success, many patients have turned to non-addictive treatment methods such as repetitive TMS (rTMS). Our physicians provide fMRI and MR Spectroscopy data specifically tailored for rTMS providers. These providers can then treat the activated areas of the brain visualized in the fMRI.

 
Sources:
1. Functional Magnetic Resonance Spectroscopy: The “New” MRS for Cognitive Neuroscience and Psychiatry Research. Jeffrey A. Stanley1, Naftali Raz; Front. Psychiatry, 12 March 2018
2. Proton Magnetic Resonance Spectroscopy for Dementia. Shiino A., Matsuda H., Asada T., Tokumaru A. (eds); Springer, Tokyo
3. The Profile of Hippocampal Metabolites Differs between Alzheimer’s Disease and Subcortical Ischemic Vascular Dementia, as Measured by Proton Magnetic Resonance Spectroscopy. Akihiko Shiino, Toshiyuki Watanabe, Yoshitomo Shirakashi, Emi Kotani, Masahiro Yoshimura, Shigehiro Morikawa, Toshiro Inubushi, Ichiro Akiguchi; Epub, February 8, 2012


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